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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIK2
All Species:
19.7
Human Site:
T425
Identified Species:
39.39
UniProt:
Q13002
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13002
NP_068775.1
908
102583
T425
K
G
K
P
A
N
I
T
D
S
L
S
N
R
S
Chimpanzee
Pan troglodytes
Q5IS46
956
107246
T417
S
D
T
L
F
N
T
T
L
V
V
T
T
I
L
Rhesus Macaque
Macaca mulatta
XP_001086762
908
102976
T425
K
G
K
P
A
N
I
T
D
S
L
S
N
R
S
Dog
Lupus familis
XP_539059
898
101336
T415
K
G
K
P
A
N
I
T
D
S
L
S
N
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P39087
908
102468
T425
K
G
K
P
A
N
I
T
D
S
L
S
N
R
S
Rat
Rattus norvegicus
P42260
908
102452
T425
K
G
K
P
A
N
I
T
D
S
L
S
N
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506390
892
100577
V419
L
S
N
R
S
L
I
V
T
T
I
L
E
E
P
Chicken
Gallus gallus
P19439
487
54337
P47
R
G
P
E
E
N
L
P
S
L
T
V
T
T
I
Frog
Xenopus laevis
Q91755
285
32023
Zebra Danio
Brachydanio rerio
XP_690040
906
102334
N453
W
N
S
N
T
G
L
N
L
T
D
S
N
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03445
991
111650
Y474
A
S
A
S
T
G
D
Y
D
R
N
H
T
Y
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34299
962
108124
Q452
A
Q
H
S
R
K
S
Q
N
D
H
K
D
N
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.6
93.9
96.4
N.A.
99
99.1
N.A.
95.2
24.2
30.2
74.6
N.A.
32.7
N.A.
32.3
N.A.
Protein Similarity:
100
59.9
96.3
96.6
N.A.
99.5
99.5
N.A.
96.3
36.3
30.8
87.2
N.A.
51.5
N.A.
52
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
6.6
13.3
0
13.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
26.6
26.6
0
33.3
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
42
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
50
9
9
0
9
0
9
% D
% Glu:
0
0
0
9
9
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
17
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
9
0
0
9
17
% I
% Lys:
42
0
42
0
0
9
0
0
0
0
0
9
0
9
0
% K
% Leu:
9
0
0
9
0
9
17
0
17
9
42
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
9
0
59
0
9
9
0
9
0
50
9
0
% N
% Pro:
0
0
9
42
0
0
0
9
0
0
0
0
0
0
9
% P
% Gln:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% Q
% Arg:
9
0
0
9
9
0
0
0
0
9
0
0
0
42
0
% R
% Ser:
9
17
9
17
9
0
9
0
9
42
0
50
0
0
42
% S
% Thr:
0
0
9
0
17
0
9
50
9
17
9
9
25
9
0
% T
% Val:
0
0
0
0
0
0
0
9
0
9
9
9
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _